Tag Archive 'Cure'

Dec 08 2011

A Monkey Experiment Paves the Way Towards HIV Functional Cure

Published by admin under Health Fitness

Philipsburg, Sin Maarten (PRWEB) December 07, 2011

The International Workshop on HIV Persistence, Reservoirs & Eradication Strategies” is supported by the American National Institute of Health (NIH) and the French Agency for AIDS Research (ANRS).

On this second day of the workshop, a breakthrough towards HIV functional cure was reported by Doctor Andrea Savarino and his team from the Italian Istituto Superiore di Sanita (Rome).

A functional cure is a situation where some HIV genetic material remains in the body but no viral replication is found in the absence of antiretroviral therapy (ART). Usually, discontinuation of ART leads to viremia rebound due to the persistence of long-lived HIV reservoirs.

The experiment used macaques infected with the simian counterpart of HIV named SIVmac251.

Eighteen animals received ART and, in some cases, anti-reservoir agents including five monkeys enrolled in a pilot study of a multidrug ART regimen in combination with auranofin (selectively killing memory T-cells) and the glutathione synthesis inhibitor buthionine sulfoximine (BSO) previously shown to facilitate elimination of the infected cells.

The difference between the viral RNA set point before and after the treatment period was positively correlated with the number of drugs potentially acting against the viral reservoir that the monkeys had received. Extremely low viral set points (These data show for the first time that anti-reservoir strategies may result in spontaneous control of viral load in the chronic phase of infection, and pave the way towards a functional cure for AIDS.

About the workshop: the “International Workshop on HIV Persistence, Reservoirs & Eradication Strategies” is held at the Westin Sin Maarten Hotel, Philipsburg, December 6-9, 2011. It is a closed meeting where participants are selected for their committment in HIV persistence research. Website: http://www.informedhorizons.com/persistence2011

About Dr Savarino laboratory: Program for HIV eradication, Dept of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy.

Animals were housed at Bioqual, Inc., Rockville, Maryland (http://www.bioqual.com), according to international ethical standards.

Press contact: Alain Lafeuillade, MD, chairman. Workshop Secretariat, Westin Sin Maarten Hotel; Philipsburg; Ph: (721) 20543-6700; email: lafeuillade(at)orange(dot)fr

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Nov 04 2011

AVENUE

Published by admin under Sports Bra

AVENUE® – Plus Size Retailer – Partners with Susan G. Komen for the Cure®











Hope Charm Bracelet


Rochelle Park, NJ (Vocus) October 13, 2010

AVENUE®, a women’s plus-size retailer and premier brand in the Redcats portfolio, is proud to announce today its partnership with Susan G. Komen for the Cure®.

AVENUE® is the first-ever plus-size specialty store retailer to join forces with Komen for the Cure in support of its promise to save lives and end breast cancer forever. Between October 17th and October 30th, AVENUE® will host a full-scale breast cancer awareness program that will reach out to every customer both in-store and via emails, as well as on Avenue.com. Visitors to Avenue.com will find a list of events that benefit “Komen for the Cure” that will be promoted during the campaign.

And what’s more, during the special two-week breast cancer awareness event, two limited edition products benefiting Komen for the Cure will be offered to AVENUE® customers: 2-piece knit socks featuring the Susan G. Komen for the Cure® Running Ribbon logo ($ 4.50) and a Hope Charm Bracelet ($ 7.90) – with a minimum of $ 3 per item sold going directly to Komen. The knit socks and bracelet can both be purchased in any AVENUE® store, as well as online at Avenue.com. In addition, $ 1 will be donated for each bra and shapewear item sold in the AVENUE® stores during this event; customers will have the opportunity to make direct donations of $ 1, $ 3 or $ 5 at the checkout register.

“I, like so many women, personally know friends and family touched by breast cancer,” said Dawn Robertson, CEO of AVENUE®. “We at AVENUE® believe a strong partnership with Susan G. Komen for the Cure® can make a difference in our customers and their families’ lives.”

“The Susan G. Komen for the Cure family is excited to be partnering with Avenue during October,” said Katrina McGhee, executive vice president and chief marketing officer for Susan G. Komen for the Cure. “The awareness Avenue is helping to bring to their employees and customer base through their campaign is critical in helping us communicate the importance of early detection for breast cancer while also raising important funds so our work can continue.”

AVENUE® is a specialty retailer of plus-size women’s fashion apparel, footwear and accessories featuring AVENUE® brand merchandise in 450 AVENUE® stores, as well as on the AVENUE® website http://www.avenue.com.

About Avenue

With over 400 stores and online at avenue.com, AVENUE®, the nation’s leading specialty retailer, provides stylish, high-quality fashion for curvy women in sizes 14-32. AVENUE® offers a wide selection of apparel from career to casual, as well as a collection of accessories, hosiery and intimate apparel. AVENUE® is a Redcats USA brand.

About Redcats USA

Redcats USA is a dynamic, multi-channel, web-driven home-shopping leader, with numerous successful brands in its portfolio: AVENUE®, Woman Within®, Jessica London®, Roaman’s®, KingSize®, and BrylaneHome® sold on OneStopPlus.com®, The Sportsman’s Guide® and The Golf Warehouse™. Redcats USA offers a wide range of value and quality driven merchandise categories, including men’s and women’s plus-size apparel, home and lifestyle products, and sporting goods/outdoor gear. Redcats USA is a Redcats company. For any further information: Redcats.com

About Susan G. Komen for the Cure®

Nancy G. Brinker promised her dying sister, Susan G. Komen, she would do everything in her power to end breast cancer forever. In 1982, that promise became Susan G. Komen for the Cure, which is now the world’s largest breast cancer organization and the largest source of nonprofit funds dedicated to the fight against breast cancer with more than $ 1.5 billion invested to date. For more information about Susan G. Komen for the Cure, breast health or breast cancer, visit http://www.komen.org or call 1-877 GO KOMEN.

Contact Information

Karen Davis

Corporate PR & Communications

Redcats USA

Karen.davis(at)redcatsusa(dot)com

212-502-9315

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